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Cure Quest 

Despite being the leading cause of death by disease in children, childhood cancer treatments remain grossly underfunded. In order to support more successful and less harmful treatments, Sophia's Fund is committed to supporting research that specifically works toward a cure for childhood cancers and brain tumors.

Learn about recent research we have helped to fund:

PEACH Protocol $7,500 contributed

A new prospective treatment for two rare childhood cancers, diffuse intrinsic pontine glioma (DIPG) and recurrent neuroblastoma, will be tested in a new human clinical trial led by pediatric oncology teams at the University of Florida and Atrium Health Levine Children’s in Charlotte, N.C.

The trial will test an innovative combination of molecular-guided therapy and personalized immunotherapy. The treatments use the unique genetic information of an individual child’s cancer to design a three-pronged approach: a specifically tailored drug treatment, a cancer vaccine containing dendritic cells and adoptive T cell therapy. 

DFCI Relapsed, Refractory or Progressive Neuroblastoma  $1,500 Contributed

Dana Farber Cancer Institute & Jimmy Fund Phase 2 Randomized Study of Irinotecan/Temozolomide/Dinutuximab with or without Eflornithine (DFMO) (IND# 141913) in Children with Relapsed, Refractory or Progressive Neuroblastoma.

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